Salvia Extract 40X

Salvia divinorum, or “Salvia divinorum plants for sale,” is a perennial herb of the largest genus of plants in the Labiatae (mint) family. Native to the cloud forest regions of the Sierra Mazateca in Oaxaca, Mexico, it typically grows in ravines and other high-altitude, humid areas. Salvia divinorum plants can reach over one meter in height and have large green leaves, hollow square stems, and white flowers with purple calyces.

The Salvia genus is a member of the tribe Mentheae and contains many varieties of sage species. As well as Salvia divinorum, other common species are Salvia officinalis, or common sage, and Salvia hispanica which produces edible Chia seeds. Many of the Salvia species are used for ornamental purposes or herbal remedies. There are about 1000 species of Salvia worldwide, but currently, only Salvia divinorum holds psychoactive properties.

Although not widely used, Salvia divinorum is a potent psychedelic characterized by unique visionary experiences. It shows great potential for treating pain and addiction, as well as depression—whether in traditional Mazatec ceremonies or more clinical, Western settings. Many people have also found it useful for personal growth.

Dosing & method of consumption

Salvia divinorum can be chewed, smoked, or taken as a purified tincture. A threshold dose of Salvinorin A is 200mcg, while the upper limit for most people is around 1000mcg (1mg). The amount of plant material, extract, or tincture required for a single dose will depend on the strength of the product being used.

One quarter to half a gram of dried leaf is a fairly mid-level dose for smoking. It’s important to inhale the entire dose in two to three minutes, though, due to the quick metabolization of Salvinorin A in the body. A water pipe or high-temperature vaporizer can make this easier.

Keep in mind, however, that two products of allegedly the same strength may contain very different levels of Salvinorin A.

Chewing Salvia divinorum involves rolling fresh or dried leaves (rehydrated in water) into a ball or cylinder called a “quid.” The quid is kept under the tongue and chewed once every ten seconds or so for at least half an hour before its spit out. With a quid, a mid-level dose of Salvinorin A requires about 30g of fresh leaves or 2-8g of dried leaves. The chew can be sweetened with sugar or Stevia extract to help with the bitter flavor.

What To Expect From Salvia Divinorum Plants For Sale

When smoking or vaporizing Salvia divinorum, the onset happens fast, peaking within the first 180 seconds and declining after 5-30 minutes. The quid chewing method takes a bit longer. You may feel nothing for the first 15-20 minutes and any effects you do feel may be diminished by light or noise. The peak effects last 30-60 minutes. Taking a purified tincture is much like quidding, but the onset is much faster.

At low doses, Salvia divinorum can cause a tingling sensation, increased awareness of the body, and enhanced clarity or presence of mind. Higher doses are associated with a loss of self-awareness, fast-changing visuals, physical impairment or dizziness, and revelatory mystical experiences. Some other, more specific effects of Salvia divinorum include tunnel vision, the sensation of merging with or becoming objects, seeing entities or beings, hearing voices, laughing uncontrollably, and experiencing overlapping realities or worlds.

Effects

Pharmacology

Salvinorin A, the psychoactive molecule in Salvia divinorum, is considered the most potent naturally occurring psychedelic compound. It is structurally and chemically unique from most other natural psychedelics. Typical psychedelic compounds contain nitrogen, but Salvinorin A is only made up of carbon, hydrogen, and oxygen atoms. It was the first non-nitrogenous psychedelic to be identified, as well as the first psychoactive diterpene.

Receptor binding

Unlike the classical psychedelics, Salvinorin A shows no binding affinity for any of the serotonin (5-HT) receptors. Its mechanism of action lies in strong and highly selective bonds to the kappa-opioid receptors (or KORs). KOR agonists are known to cause hallucinations or visions, dissociation, and a sense of altered reality

Benefits & Risks Salvia divinorum Plants

Benefits

The Mazatec Indians of Oaxaca have long used Salvia divinorum for ceremonial purposes. In fact, it is revered as an incarnation of the Virgin Mary, and is traditionally used for healing and divination. In the Western world, more people are beginning to use this substance to treat depression, enhance their meditation practice, and connect to their spirituality.

Though there isn’t much research into the therapeutic effects of Salvia divinorum compared to other, more common psychedelics, there is some evidence that shows the compound could prove useful in treating addiction and pain, as well as understanding schizophrenia and Alzheimer’s.

Risks

Research on the safety of Salvia divinorum plants for sale is limited, but a 2003 study found pure Salvinorin A to be of “relatively low” toxicity to rodents, even at doses of up to 6400mcg—more than three times the highest known human dose and six times the maximum recommended dose. In this study, the rodents were also continually given the drug during a two-week period, which is not common for people. However, even with this chronic use, the researchers found no adverse effects. In humans, a toxic overdose is very unlikely.